New antibiotic ‘evades bacterial resistance’
A promising new weapon has emerged in the fight against drug-resistant bacteria and resultant diseases, writes Rob Mitchum.
The antibiotic cresomycin - described in Science - effectively suppresses pathogenic bacteria that have become resistant to...
Hijacking our cell enzymes to eliminate disease-causing proteins
By studying how enzymes move from one membrane compartment to another inside a cell, scientists at the University of Illinois Chicago have figured out a way to better target cellular proteins, which play a...
Diabetes drug slows growth of normal cells with cancer mutation
A common diabetes medication, metformin, slows the growth of pre-cancerous cells in the oesophagus while some metabolic conditions accelerate it, suggests a new study.
Researchers from the Wellcome Sanger Institute discovered that metformin reduced the...
Cellular ‘traffic controllers’ caught managing flow of signals from receptors
First time that individual beta-arrestin molecules are directly observed as they control receptor-mediated signals in living cells using advanced microscopy.
New findings could inform the development of better drugs for pain relief,...
Life-saving cancer drug takes a major step closer to patient care
A new drug candidate for hard-to-treat cancers, discovered at the University of Edinburgh and licensed by biopharmaceutical company Nuvectis Pharma, Inc. (“Nuvectis” or “Company”), can now begin clinical trials as announced by Nuvectis.
The compound,...
‘World-first’ immunotherapy drug designed by generative AI
British techbio innovator Etcembly has kickstarted the next generation of immunotherapies with a pipeline of best-in-class T cell receptor (TCR) therapeutics designed using generative AI.
The company’s lead therapeutic programme, ETC-101, is the world’s first...
New drugs partnership tackles lung disease
Aston University scientists are working with start-up company, Isterian Biotech, part of Cambrian BioPharma, to develop novel drugs to treat fibrotic diseases such as lung disease.
The focus of preclinical-stage biotechnology company Isterian Biotech is...
Artificial sugars enhance disease diagnosis and treatment accuracy
Scientists have found a way to create artificial sugars that could lead to better ways to diagnose and treat diseases more accurately than ever before.
Sugars play a crucial role in human health and disease,...
Trailblazing scientist is first British winner of Lifetime Achievement Award
British scientist Dame Carol Robinson has received the Lifetime Achievement Award at the European Inventor Award 2024.
The Professor of Chemistry at the University of Oxford is a trailblazer in the field of mass spectrometry...
Dual action antibiotic could make bacterial resistance nearly impossible
A new antibiotic that works by disrupting two different cellular targets would make it 100 million times more difficult for bacteria to evolve resistance, according to research from the University of Illinois Chicago.
For a...
protein cage design for advanced drug delivery systems unveiled
An international collaboration between researchers at Durham University (UK) and the Malopolska Centre of Biotechnology, Jagiellonian University (Poland) has resulted in the generation of a novel artificial protein cage that holds great promise as...
Antibacterial material restores efficacy of antibiotics against resistant bacteria
Resistant bacteria can regain susceptibility to antibiotics when the treatment is combined with a material equipped with antibacterial peptides.
The study, performed in a laboratory environment, shows that antibiotics can achieve a 64-fold increase in...
Tiny sea microbes could unlock new cures
Off the coast of Spain, studies of the marine microbiome are opening new doors for pharmacology, writes Claudia Alemañy Castilla.
The island of Tabarca, near Alicante, is a tourist magnet. It’s also a working platform...
Breaking new ground in antibiotic research with neutrons
Dr Luke Clifton, Instrument Scientist at ISIS Neutron and Muon Source, explains how neutrons have emerged as a highly effective tool in the fight against AMR.
Antimicrobial resistance (AMR) has been one of the biggest...
Europe’s ‘disappearing’ generic medicines are a growing crisis
Europe’s critical medicine cabinets – in hospitals, pharmacies, and homes – are home to fewer generic medicines. These are the often-cheaper alternatives to brand name medicines, that make up 67%1 of all medicines.
Research from Teva...
Scientists create tailored drug for aggressive breast cancer
Scientists have used breast cancer cells’ weakness against themselves by linking a tumour-selective antibody with a cell-killing drug to destroy hard-to-treat tumours.
The research, published in Clinical Cancer Research by a team from King’s College...