Closing the Loop on personalised healthcare

Precision medicine using personalised treatments has entered mainstream healthcare. Closed Loop Medicine Ltd aims to level the playing field further with its drug and digital combination products. The Cambridge-based healthcare company is developing drug and...

Recruiting the right people for medical research

Clinical research is making massive strides in the way we treat illnesses, extending length and quality of life for the patient. Making the breakthroughs possible are medical researchers who rely heavily on the willingness...

Lab-grown ‘mini-stomachs’ could shed light on children’s COVID symptoms

A ‘lab-grown model’ of the human stomach, that can be used to study how infections affect the gastrointestinal system, has been developed for the first time. A UCL-led team of international scientists have built on...

Treading the path less travelled – A different approach to patient recruitment

In a previous issue, we spoke to Professor Miles Witham about his work to facilitate the participation of older people in clinical trials. Now we hear from Sarah Montague about a trial engaging homeless...

Build-up of brain proteins affects genes in Alzheimer’s disease

New research has shed fresh light on how the build-up of two proteins in the brain might affect the activity of genes involved in Alzheimer’s disease. Researchers at the University of Exeter worked in collaboration...

Thriving commercial ecosystems will help universities to keep making an impact beyond Covid-19

Throughout 2020, the life sciences sector has been in the limelight. In the effort to overcome COVID-19, the sector has put into action an unprecedented global application of expertise. The deployment of great minds,...

Supercharged natural killer cells may hold promise for cancer

A type of ‘supercharged’ immune cell could be mass-produced to help fight cancer. The researchers behind the early-stage finding, from Imperial College London, say the development could mark the next generation of cutting-edge immunotherapy treatments,...

Bacteria can develop strong immunity for protection against viruses

A new study hopes to exploit newly characterised defence systems in bacteria to compare changes to the human genome. University bioscientists have been working on the research to demonstrate the complex workings of bacterial innate...

Research deepens understanding of malaria parasite

Science carried out in Nottingham helped to form the foundation for the latest breakthrough in the global fight against malaria. Researchers in the University of Nottingham’s School of Life Sciences were responsible for the identification...

Combatting antibiotic resistance

In the UK alone, the government estimates there are currently 5,000 deaths each year because antibiotics no longer work for some infections. Worldwide, drug-resistant infections are set to kill more people than cancer and...

New research predicts a positive future for biosimilars

The prospect of reducing treatment costs for payors supports a positive future for biosimilars Biosimilar approvals in the US market still significantly lag behind Europe despite an evolving regulatory landscape and three new...

Diagnostic devices reimagined

Diagnostic devices are coming on in leaps and bounds but you may be surprised to learn that one device that’s remained much the same since the late 1950s is the colonoscope. One researcher working...

Over three million surgical operations and cancer treatments a year in England may become...

New data published by Public Health England (PHE) show that antibiotic resistant bloodstream infections continue to rise in England, with an estimated 35% increase from 2013 to 2017 (from 12,250 in 2013 to...

New material to treat wounds can protect against resistant bacteria

Researchers at Chalmers University of Technology, Sweden, have developed a new material that prevents infections in wounds – a specially designed hydrogel, that works against all types of bacteria, including antibiotic-resistant ones. The new...

Potential breakthrough in treatment of rare disease

Biotech company Actigen has initiated a clinical development programme for GNR-055, a potentially breakthrough treatment for the life-limiting, rare disease mucopolysaccharidosis II (MPS II) (also known as Hunter syndrome). Occurring in around 1 in...

Cancer cell ‘switch-off’ could aid deadly brain tumour treatment

Researchers believe they may have found a way to strengthen possible treatments for glioblastoma and reduce the speed at which the aggressive tumour progresses. Glioblastoma is the most common primary brain tumour in adults, and,...