Stanford shows that breast cancers punch tunnels into neighbouring tissue

Stanford researchers have found that malignant breast cancer cells can extend protrusions known as invadopodia to dig escape tunnels through surrounding tissue, revealing a possible new target for therapies. Cancers pose the greatest danger when...

Cellular protein factories may contribute to ageing and related diseases

Research finds that the cellular assembly line that produces proteins can stall with age, triggering a snowball effect that increases the output of misfolded proteins. In humans, clumps of misfolded proteins contribute to age-linked...

Research reveals how Tau aggregates can contribute to cell death in Alzheimer’s disease

New evidence suggests a mechanism by which progressive accumulation of Tau protein in brain cells may lead to Alzheimer’s disease. Scientists studied more than 600 human brains and fruit fly models of Alzheimer’s disease...

How chromosomes find a happy medium

By Sabrina Richards Staff writer at Fred Hutchinson Cancer Research Center Hutch scientists show how chromosomes communicate to balance crossovers during sex-cell formation Scientists at Fred Hutchinson Cancer Research Center have worked out the molecular underpinnings of...

Focus on Alzheimer’s disease 
– Hope on the horizon

Dr David Reynolds Chief Scientific Officer at Alzheimer’s Research UK Alzheimer’s Research UK is the UK’s leading dementia research charity and is dedicated to funding pioneering research to find ways to understand, diagnose, reduce risk and...

Hope as research unlocks the secrets of heart disease

By Frances Griss Since the beginning of the 1960s, deaths from heart disease in the UK have halved so that today only 26% of people have a cause of death attributable to the condition, compared with...

The search for new antimicrobials

Few issues are more pressing than the global problem of antibiotic resistance, so we speak to Professor Mathew Upton, about his work searching for new antibiotics. “For so long now, antibiotics have been seen as...

Research finds three major failings in some apps used for the diagnosis of skin...

In the scramble to bring successful apps for the diagnosis of skin cancer to market there is a concern that a lack of testing is risking public safety, according to research led by the...

Surface research could help control infection

Another front in the war against infection is the introduction of antimicrobial surfaces into hospitals. By making the environment more hostile to pathogens such as Clostridium difficile and Staphilococcus aureus there will be less...

Research offers hope

There is hope in the battle against drug-resistant drugs, though. For example, a newly discovered antibiotic, produced by bacteria from a cystic fibrosis patient, could be used to treat cases of drug-resistant tuberculosis (TB),...

Former Prime Minister takes on key Dementia research role

Former Prime Minister David Cameron has become the new President of Alzheimer’s Research UK, the UK’s leading dementia research charity. Mr Cameron made dementia a major focus of his time in office, launching the Prime...

Researchers are making great strides

We have made great strides in the fight against heart disease over the past 50 years. Since 1961, when the British Heart Foundation was established, the annual number of deaths from CVD in the...