Amsbio reports that its iMatrix-511 recombinant laminin product has been cited in a recent paper** from researchers at the Stanford University School of Medicine, Stanford, CA, USA as a pivotal tool for stem cell culture and blastoid formation.
This groundbreaking study describes how human blastoid models (stem-cell derived blastocyst-like structures) were used to investigate how human-specific LTR5Hs elements regulate early embryonic development. It provides new unique insights into epiblast differentiation and early embryogenesis.
iMatrix 511 is a highly purified and refined version of the human recombinant laminin-511 E8 fragment expressed by CHO-S cells. Widely regarded as a gold standard for stem cell culture, iMatrix-511 is an innovative cell culture matrix which permits ES/iPS cells to be maintained in feeder-free culture conditions. Immediately available from stock– iMatrix-511 also enables the passaging of single cells and is proven to provide greater adhesion than full-length Laminin, Vitronectin or Matrigel.
iMatrix-511 can also be used together with Amsbio’s StemFit cell culture media and CELLBANKER cryopreservation series as part of an expanded Stem Cell Synergy solution for ES/iPS cell cultures.
To read more about the Stanford University research study please visit https://www.nature.com/articles/s41586-025-09571-1.
For further information about iMatrix-511 recombinant laminin products please visit https://www.amsbio.com/imatrix-recombinant-laminin-511/ or contact Amsbio on +31-72-8080244 / +44-1235-828200 / +1-617-945-5033 / info@amsbio.com.
