BIOMEDICAL

Polar microbes influence climate change as frozen ecosystems thaw

Microbes across Earth’s coldest regions are becoming more active as glaciers, permafrost and sea ice thaw, accelerating carbon release and potentially amplifying climate change, according to a new international review from McGill University. Drawing on data from polar and...

A poorly ‘cleaned’ brain increases psychosis risK

How can we explain the onset of psychotic symptoms characteristic of schizophrenia? Despite their major and often irreversible impact on intellectual abilities and autonomy, the biological mechanisms that precede their emergence remain poorly understood. A team from the Department of Psychiatry...

How structural biology is shaping the future of vaccines

By Professor Sir Dave Stuart FRS, Director of Life Sciences at Diamond Light Source and MRC Professor of Structural Biology at the University of Oxford. Vaccines have saved 154 million lives in the last 50 years - that is up...

World-first transplant technology wins 2025 MacRobert Award

A University of Oxford spinout has won the £50,000 MacRobert Award, the longest running and most prestigious prize for UK engineering innovation, for its life-saving technology that is supporting more organ transplants and helping to cut waiting lists. OrganOx has...

Found: protein that helps cancer spread – and could stop it!

Biomedical scientists have discovered a protein called SAS-6 that controls how cells divide can stave off the spread of cancer.  SAS-6 makes cells grow more and longer cilia – tiny antennae that sense their surroundings. These cilia activate a pathway...

Nanoflowers could support brain health

Novel nanomaterials may protect against neurological diseases through their antioxidant abilities. At Texas A&M AgriLife Research, a new branch of brain science is blooming at the molecular scale – with nanoflowers. A study published in The Journal of Biological Chemistry demonstrated...

Have we hit peak oncology? Navigating the state of cancer R&D in 2025

Recent levelling-off signals a maturing sector, says Ian Lloyd, Senior Director, Citeline. The pharmaceutical R&D ecosystem has never been bigger. The global drug pipeline now approaches 24,713 active targets, with numbers increasing 145% from January 2010 to January 20251 – a...

Autism: unravelling the defective neural roots behind social connection

Scientists have identified a brain circuit which is central to the social difficulties experienced by people with autism spectrum disorders. From birth, human survival depends on the ability to engage with others. This ability, which is essential for development, seems...

Microplastic fragments in brain arteries put world on ‘red alert’

The threat of microplastics – tiny fragments of plastic pollution – discovered inside the arteries that feed the human brain need urgent investigation, say campaigners. Alarming new scientific findings have come from a preliminary study led by Dr. Ross Clark,...