A new blog has been published by Amsbio comparing the benefits of its CELLBANKER® range of cryopreservation solutions with ‘homebrew’ cryopreservation media.
Homebrew cryopreservation media are do-it-yourself solutions, commonly using a mixture of DMSO, a serum (such as FBS), and a basal growth medium. These mixtures are often favored because of their lower upfront cost or to meet specific lab needs, but the optimal formulation depends heavily on the cell line’s sensitivity.
From academic research to GMP manufacturing, reproducibility, and reliability in cryopreservation are critical. While homebrew cryopreservation mixtures can work, variability between serum lots and preparation methods can lead to inconsistent results. Each batch needs revalidation, and contamination risks increase with manual handling. By comparison, CELLBANKER® eliminates that uncertainty. Each batch is manufactured under strict quality control using chemically defined, sterile components to deliver the same performance every time. It is also completely ready-to-use, removing the need for in-lab mixing and reducing contamination risk.
In addition, while CELLBANKER® provides an animal-free, chemically defined, sterile, and traceable solution that supports regulatory compliance and long-term sample integrity – homebrew serum-based media can introduce biological variability. The authors show how for sensitive cells such as primary cells, iPSCs, or organoids, the level of consistency provided by CELLBANKER® results in better cell viability and reproducibility post-thaw.
Beneficially the CELLBANKER® range also includes a GMP-grade formulation available at a competitive price point, allowing researchers to use clinical-grade materials early in development without a steep cost jump. This seamless transition from research to clinical manufacturing helps maintain consistency, simplifies validation, and avoids the expensive requalification often required when switching suppliers later in the process.
This informative blog also includes customer technical paper references and CELLBANKER® testimonials from internationally renowned organoid and stem cell research and development groups. To read the blog in full please visit https://www.amsbio.com/news/cellbanker. For further information on the CELLBANKER® range of cryopreservation solutions please visit https://www.amsbio.com/cryopreservation/ or contact Amsbio on +31-72-8080244 / +44-1235-828200 / +1-617-945-5033 / info@amsbio.com.
