Flu outbreaks teach valuable lessons
A study of influenza is also helping scientists to learn more about the immune system.
A four-year study of 1,414 unvaccinated people across England found that 43 per cent had immune cells that protected them...
Everyday tablet could lead to relief for cancer sufferers
Another example of immunology at work is new research that suggests that giving cancer patients aspirin at the same time as immunotherapy could dramatically boost the effectiveness of the treatment.
Francis Crick Institute researchers, funded...
Tackling rheumatoid arthritis
Professor Ehrenstein’s specialism is rheumatoid arthritis and he said: “Because we are becoming much better at targeting our treatments, we are much better at suppressing symptoms. We do not have a cure for rheumatoid...
Better understanding of immunology offers hope for the future
Recent years have seen dramatic strides being taken in the science of immunology – the capacity to direct the body’s natural defences against specific illnesses and conditions.
So dramatic have the strides been that scientists’...
Cell therapy manufacturing
Regenerative medicine and cellular therapies have the potential to impact many different areas of unmet medical need. There are many human diseases which have either inadequate or no treatment options. One of the main...
Cell therapy manufacturing –making the future now
There is no mistaking the sure but steady revolution happening in cell therapy. With the long-held promise now rewarded with greater funding, investment and belief, the change in gear has been dizzying.
However, this is...
Cell therapy manufacturing industry takes big steps forward
Cell Therapy production across the world has made some significant advances in recent months, with investment in manufacture announced and exciting research suggesting new applications.
The industry in the UK has taken a step forward...
Setting up a Bio Science business – Intellectual Property
This is the first in a series of short articles on aspects of starting a bio science business
Although some very successful service businesses have been built without specific intellectual property and instead have relied...
Characterization of CRISPR/Cas9introduced Mutations using the Guide-it™ Indel Identification Kit
Streamlined method for characterizing the variety of indels introduced by genome editing technologies: Ideal foridentifying indels introduced by CRISPR/Cas9 genome editing in a cell population
A complete kit containing all of the components needed...
CRISPR/CAS9: It’s a good time for gene editing – don’t ruin your experiments with...
Biomedical researchers have long sought the “magic wand” for targeted genome editing in an attempt to affect phenotypic outcome. A number of methods allow manipulation of gene function, including viral vectors, homologous recombination, RNAi,...
MRC Harwell: New opportunities for partnerships
The Mary Lyon Centre at MRC Harwell has developed into a centre of excellence for thecreation, breeding, archiving and phenotyping of the laboratory mouse. It continues toadvance, harnessing new technologies, such as those in...
Genome-editing tools offer Pharmaceutical Companies new opportunities for drug discovery and development
Advances in genome editing technologies will beanother powerful tool available to scientists inJanssen R&D in their efforts to discover and develop safeand effective medicines.
By Inès Royaux, PhD
Senior Scientist at Janssen R&D
The ability to...
Genome editing technology moves forward
Editing the human genomeis a ground-breaking technique which is raising the hopes of millions of people afflicted by inherited disease.
Research has already made significant advances in possible therapies for diseases as diverse as sickle-cell...
DEPArray™ Technology unleashesthe power of NGS
Next-Generation Sequencing (NGS) has the potential to revolutionize clinical oncology by providing direct, actionable molecular information about tumor cells. Such information could be used to stratify patients for appropriate clinical trials assignment, select of...
Advances in analytical characterisation of biosimilars
The substantial improvement in the power of analyticalmethods to compare different versions of a givenprotein molecule should be taken into account whenconsidering the need for clinical studies for designation ofbiosimilarity. Arguably, demonstration of comparative...
The growth in the global biosimilars market
The growth in the global biosimilars market is continuing to accelerate ata remarkable rate, drivenby an increasing interest in cheaper versions of major drug brands as health services try to reduce spiralling drug bills.
One...