Potential breakthrough in treatment of rare disease
Biotech company Actigen has initiated a clinical development programme for GNR-055, a potentially breakthrough treatment for the life-limiting, rare disease mucopolysaccharidosis II (MPS II) (also known as Hunter syndrome). Occurring in around 1 in...
New treatment on horizon against ‘parasite’ mitochondria
A groundbreaking study has solved the old enigma in mitochondrial DNA disorders and advances the prospect of enhanced treatments for patients.
It not only resolves a long-standing conundrum in the molecular pathology of mitochondrial disease,...
DMT-assisted therapy: changing the way we think about depressive disorders
A ‘spirit molecule’ from the Amazon could be a game changer in the treatment of major depressive disorders. Dr Carol Routledge, of Small Pharma, talks to Karen Southern about her pioneering work with DMT.
Psychedelic...
Personalised medicine: driving a need for greater diversity
Kate Shaw, CEO of Innovative Trials, investigates one of the biggest challenges facing clinical research today.
Personalised medicines, particularly gene and cell therapies, offer new opportunities for treating serious conditions such as muscular dystrophy, cystic fibrosis...
Lab-grown ‘mini-stomachs’ could shed light on children’s COVID symptoms
A ‘lab-grown model’ of the human stomach, that can be used to study how infections affect the gastrointestinal system, has been developed for the first time.
A UCL-led team of international scientists have built on...
Bacteria can develop strong immunity for protection against viruses
A new study hopes to exploit newly characterised defence systems in bacteria to compare changes to the human genome.
University bioscientists have been working on the research to demonstrate the complex workings of bacterial innate...
Light therapy helmet could help dementia patients
A new infrared light therapy has the potential to help people with dementia.
A pilot study recently investigated how transcranial photobiomodulation therapy (PBM-T) –transferred through a specially adapted helmet -- could boost memory, motor function...
Shaping the science of oncology
Dr Fiona McLaughlin is the new Chief Scientific Officer of Avacta’s Therapeutics Division. She talks to Karen Southern about her mission to develop first and best-in-class cancer drugs.
From the day that Dr McLaughlin –...
TWO NEW FORMS OF THERAPY GIVE HOPE WHEN BLOOD CANCER RETURNS AND BOWEL CANCER...
Scientists trial new way to boost CAR T-cell therapy
Cancer Research UK is collaborating with Aleta Biotherapeutics to trial a new therapy that reboots a treatment for some people whose blood cancer starts to come back.
The new...
£7m invested in fight against antimicrobial resistance
Phico Therapeutics Ltd, a biotechnology company developing engineered phage technology as the basis of a new generation of antibiotics to overcome antibacterial resistance, has announced £7m in new investment.
The financing was led by growth...
UK ‘Octopus’ trial tackling multiple sclerosis is a world first
A ground breaking mega-trial for progressive multiple sclerosis will be launched in the UK later this year.
Octopus, so called because of its multiple arms, is a revolutionary clinical trial that will transform the way...
Pioneering technique paves way for fast and cheap fabrication of rapid medical diagnostic tools
Breakthrough promises to democratise microfluidics and lab-on-a-chip technology, benefiting resource-poor countries and settings.
New technology developed by the University of Bristol has the potential to accelerate uptake and development of on-chip diagnostic techniques in parts...
CRYONISS EARNS COVETED MHRA QUALITY MARK
Experts in biological sample, and medicinal product, storage and logistics management, CRYONISS offers a comprehensive storage service from ambient down to vapour phase liquid nitrogen.
The Cheshire-based team has a wealth of experience in supporting...
Automated drug discovery platform brings about paradigm change for research
Bringing a single new drug to market takes years of research and costs billions – with the COVID-19 pandemic highlighting even more how critical it is to accelerate this process. The high costs and...
Clinical trials for gene and cell therapies
In early 2020, the Cell and Gene Therapy Catapult (CGTC) reported that there were 127 ongoing trials in advanced therapy medicinal products (ATMP) in the UK. This represented 12 percent of trials globally, helping...
WEAPONISING THE FIGHT AGAINST ANTIBIOTIC RESISTANCE
Could faecal transplants be an effective weapon in the fight back against antibiotic resistance? A research team at Guy’s and St Thomas’ NHS Foundation Trust intends to find out, once and for all.
By HELEN...