Diabetes drug slows growth of normal cells with cancer mutation

A common diabetes medication, metformin, slows the growth of pre-cancerous cells in the oesophagus while some metabolic conditions accelerate it, suggests a new study. Researchers from the Wellcome Sanger Institute discovered that metformin reduced the...

Dual action antibiotic could make bacterial resistance nearly impossible

A new antibiotic that works by disrupting two different cellular targets would make it 100 million times more difficult for bacteria to evolve resistance, according to research from the University of Illinois Chicago. For a...

Artificial sugars enhance disease diagnosis and treatment accuracy

Scientists have found a way to create artificial sugars that could lead to better ways to diagnose and treat diseases more accurately than ever before. Sugars play a crucial role in human health and disease,...

AI unlocks virus protein structures for the first time

Scientists are pioneering the use of machine-learning artificial intelligence software to investigate viruses, revealing never-before-seen viral mechanisms which yield fundamental insights and pave the way for vaccine development. The research – published in Nature and led...

Enzyme discovery paves way for greener cancer treatments

Scientists from The University of Manchester have uncovered a more efficient and sustainable way to make peptide-based medicines, showing promising effectiveness in combating cancers. Peptides are comprised of small chains of amino acids, which are...

Trailblazing scientist is first British winner of Lifetime Achievement Award

British scientist Dame Carol Robinson has received the Lifetime Achievement Award at the European Inventor Award 2024. The Professor of Chemistry at the University of Oxford is a trailblazer in the field of mass spectrometry...

Scientists create tailored drug for aggressive breast cancer

Scientists have used breast cancer cells’ weakness against themselves by linking a tumour-selective antibody with a cell-killing drug to destroy hard-to-treat tumours. The research, published in Clinical Cancer Research by a team from King’s College...

Chicken feathers to deliver chemotherapy drugs and repair enzymes

A new method of drug delivery using proline, an amino acid found in chicken feathers and skin tissue, could be used to limit the side effects of chemotherapy and repair important enzymes, new research...

Breakthrough in creating cyclic peptide opens the way for new antibiotics

A discovery by scientists at King’s College London could speed up efforts to produce new antibiotics in the fight against antimicrobial resistance. In a paper published in the Journal of the American Chemical Society, scientists...

How efficient logistics can change the lives of rare disease patients

Dr. Danial Arkwell, Head of Global Key Accounts, Pharma, at Envirotainer, highlights the vital role of efficient logistics in getting orphan drugs to patients in desperate need. There are approximately 8,000 rare diseases in the...

Unlocking potential: The impact of CRISPR in organoid research

This exclusive article is by Dr. Ralph Vogelsang, Senior Director of Business Development & Licensing, ERS Genomics. Conventional drug discovery models, such as animal models or human cell lines, often fail due to their divergence...

New antibiotic ‘evades bacterial resistance’

A promising new weapon has emerged in the fight against drug-resistant bacteria and resultant diseases, writes Rob Mitchum. The antibiotic cresomycin - described in Science - effectively suppresses pathogenic bacteria that have become resistant to...

Europe’s ‘disappearing’ generic medicines are a growing crisis

Europe’s critical medicine cabinets – in hospitals, pharmacies, and homes – are home to fewer generic medicines. These are the often-cheaper alternatives to brand name medicines, that make up 67%1 of all medicines. Research from Teva...

Tiny sea microbes could unlock new cures

Off the coast of Spain, studies of the marine microbiome are opening new doors for pharmacology, writes Claudia Alemañy Castilla. The island of Tabarca, near Alicante, is a tourist magnet. It’s also a working platform...

Breaking new ground in antibiotic research with neutrons

Dr Luke Clifton, Instrument Scientist at ISIS Neutron and Muon Source, explains how neutrons have emerged as a highly effective tool in the fight against AMR. Antimicrobial resistance (AMR) has been one of the biggest...

£25m funding for future vaccine development

Three ambitious research projects designed to build our understanding of viruses and how the immune system reacts to different challenges will share £25 million in new funding from UK Research and Innovation (UKRI). Tackling Infections...