1 in 6 children ‘neurodivergent’ as autism numbers quadruple

The number of children diagnosed with Attention-deficit /hyperactivity disorder (ADHD), autism and other neurodevelopmental disorders classifying them as ‘neurodivergent’, has rocketed in both the UK and US.  “Now, one in six children in the US...

Unravelling the Maths Behind Wiggly Worm Knots

Wriggly worms could help create a world of ‘shapeshifting’ robotics. Catherine Barzler, of Georgia Tech, investigates. For millennia, humans have used knots for all kinds of reasons — to tie rope, braid hair, or weave...

Hope in the treatment of kidney disease

Research into kidney disease is offering hope for sufferers in the years to come. One piece of research by a Kidney Research UK-funded scientist has made some vital advances in helping to understand a virus...

A historical case with modern significance

In the medical field, spectroscopy technology is being used for research into 470-year-old bones which may have relevance to modern-day sufferers of the bone condition rickets. The technology helped scientists confirm that many sailors who...

Sizzling breakthrough for 3D meat

A 4oz steak has been ‘lab-grown’ using a digital design file. Israeli firm MeaTech 3D Ltd. cultivated the bio-printed steak using real fat and muscle cells. The cells were produced using an advanced process that...

Tackling the trillion dollar Alzheimer’s disease

It’s almost impossible to conceive the complexity that lies ahead in the challenge to address Alzheimer’s disease. But, picture standing in front of an old mansion house, completely overgrown with ivy, trees, and shrubs....

The scientific, political and economic implications of COVID-19: an insider’s perspective

It is widely assumed that the life science industry performed well off the back of the COVID-19 pandemic, with the demand for assays and molecular tools driving unprecedented sales to support global research. This...

Market place becoming more competitive

Popular as this technology is, there are others vying for a niche in the same markets with equal claims on convenience and popularity with patients and clinicians alike. In 2011/12 Garcia-Diaz et al studied patient...

Clinical trials for gene and cell therapies

In early 2020, the Cell and Gene Therapy Catapult (CGTC) reported that there were 127 ongoing trials in advanced therapy medicinal products (ATMP) in the UK. This represented 12 percent of trials globally, helping...

Company announces MSA drug research projects

Drug company Evotec has entered into three novel research projects aimed at coming up with new discoveries for the treatment of Multiple Sclerosis. Supported by research funds from the German Federal Ministry of Education and...

Research reveals how Tau aggregates can contribute to cell death in Alzheimer’s disease

New evidence suggests a mechanism by which progressive accumulation of Tau protein in brain cells may lead to Alzheimer’s disease. Scientists studied more than 600 human brains and fruit fly models of Alzheimer’s disease...

2022: The year for UK Life Sciences?

Charles Walford, Senior Development Director and Head of Life Sciences, Stanhope PLC, considers the opportunities and challenges facing the UK’s life sciences ecosystem. The past two years have propelled life sciences into the mainstream. The...

Stay future-ready: Running parallel operations with a CDMO during clinical trials

Bringing a drug candidate through clinical trials is a challenging and high-risk process, since only 10% of candidates actually reach final approval. Both established pharma companies and small startups are often faced with this...

Inhaler technology developing all the time

For many years, respiratory diseases have been treated with drugs delivered via inhalers. Sufferers from asthma and chronic obstructive pulmonary disease (COPD) are extremely familiar with the technique but research is now advanced on using...

Robust, ready-to-use cell-based potency assays for biosimilar development

By Jane Lamerdin, Ph.D., Abhishek Saharia, Ph. D.
DiscoveRx Corporation, Fremont, CA 94538, USA Biosimilars are defined as drugs that are “highly similar” to or “interchangeable” with an approved biologic. The lack of a clearly defined...

Characterization of CRISPR/Cas9introduced Mutations using the Guide-it™ Indel Identification Kit

Streamlined method for characterizing the variety of indels introduced by genome editing technologies: Ideal foridentifying indels introduced by CRISPR/Cas9 genome editing in a cell population A complete kit containing all of the components needed...