Growing the UK cell and gene therapy industry
Cell and gene therapies are at the very cutting-edge of medical research and the creation of the Cell Therapy Catapult’s state-of-the-art £55 million manufacturing centre at the Stevenage Bioscience Catalyst, will help Britain be...
Biosimilars – What are the critical regulatory milestones during development and registration?
The ever increasing complexity of regulations and drug approval pathways has converted regulatory intelligence into one of the key assets during any kind of drug development.
This situation is even more pronounced in the case...
£45M to advance gene therapy treatment of chronic kidney diseases
The University of Bristol has secured a £45million deal to advance its ground-breaking gene therapy technology for chronic kidney diseases.
The commitment, made by healthcare company Syncona Ltd to Bristol spin-out Purespring Therapeutics, aims to...
Breakthroughs in Diagnostics: Genome Sequencing for proactive paediatric screening
By Dr Madhuri Hegde, FACMG - SVP and Chief Scientific Officer, Revvity, Inc.
Next generation of genomics
Technological breakthroughs have ushered in the next generation of genomics, enabling clinicians to deliver hyper-personalised, evidence-based prevention and treatment...
Critical Factor for Industrializing Cell Therapies:
Quality Attributes and Quality Assurance of the Manufacturing Raw Materials
Slowly but progressively more Advanced Therapy Medicinal Products (ATMP), including Cell Therapy Products, are reaching the market and a significant number are getting closer to...
Product Characterization for Cell Therapy GMP Manufacturing
The specifications, QC and release testing of cell therapy products can make the difference between success and failure.
Stefanos Theoharis, Suncana Kern and Christine Guenther, apceth GmbH & Co. KG
All manufactured products require measurable parameters,...
Colon Cancer Cells Use Mysterious RNA Strands to Avoid Cell Death
New study paves way for novel therapeutics
Researchers from Case Western Reserve University School of Medicine have discovered how unusually long strands of RNA help colon cancer cells avoid death, allowing unregulated growth. Unlike other...
New clinical study into R-ketamine use for Treatment Resistant Depression
A clinical study to evaluate the safety and efficacy of PCN-101 (R-ketamine) has entered a new phase.
R-ketamine is a stereoisomer of ketamine being developed for therapeutic treatment of psychiatric disorders such as Treatment Resistant...
Vericel: Improving multicellular therapy through advanced manufacturing
Founded in 1989, Vericel (formerly Aastrom Biosciences) is dedicated to the development of patient-specific expanded cellular therapies for use in the treatment of patients with severe diseases and conditions.
The company currently markets two cell...
Bolder Faster Stronger
How far can we go in the battle against illness? Earlier this year, Austrian researchers came up with the startling suggestion that life should be regarded as beginning at sixty five.
Researchers at the International Institute...
The age of Cell Therapy
Industry that takes advantage of pioneering research. For a cutting-edge technology, cell therapy has a surprisingly long history. Indeed, the idea of injecting living cells into a patient originated in the nineteenth century.
Although scientists’ early...
Replace FBS with Human Platelet Lysate
The manufacture of clinical-grade cellular products often requires ex vivo culture and expansion of human cells.
Fetal bovine serum (FBS) is frequently used as a supplement to basal cell culture media during expansion; however, its...
Looking for a partner for your biosimilar clinical trial?
BioKinetic Europe is one of the UK’s leading early phase clinical research organizations with experience in over 400 clinical trials. Our Phase I portfolio comprises BE/BA studies, SAD/MAD/Proof of Concept, TQTc, DDI, vaccine and...
Climate Change – and the challenges facing mankind
Climate change is one of the biggest challenges facing mankind. Always has been, always will be, and that means that big changes lie ahead.
Many of those changes will impact on the work of scientists...
Lifestyle and drug regimes impact on breast cancer statistics
White women could substantially reduce their risks of developing breast cancer by taking a leaf out of the books of women from other ethnic groups. A study led by Dr Toral Gathani from the University...
Closing the gap on mental health
A UK Department of Health report called Closing the Gap: Priorities for essential change in mental health, has continued work to give mental health equal priority with physical health. The department says that in many...